Objective: To evaluate serovar and antimicrobial resistance patterns of Salmonella from healthy, diseased and necropsied cows and calves in this observational study. spp isolated Methods: Nineteen isolates recovered from feces and tissues of salmonellosis-affected animals soaf mtwpole cdo m4 mtimerecsi awl iftahr mans iinn tnerovrathl -oefa 2s tm oof nIrthan. .T Ihne sseacmonpdle sp airntc oluf dthede sctauldvye,s ’t hfeec tewso, afadrumlts cwowerse’ ffeecceasl ,s afemepdlse, sw caotlelre,c mtedil kfr ofimlte cras,l vaensd a nmdi lpke frei-dp taor tcuarliveenst. cFoiwvse. SNaol mSaolnmelolnae lwlae rwe aiss orleactoevde frreodm f r3o3m2 water, feed, milk filers and milk fed to calves. Results: Salmonella Typhimurium was the most frequently isolate among all sero-groups. S. Dfour bthlien was only accounted for 8% (two out of 24) of isolates. Isolated Salmonella strains were used suggestEiRnIgC tPhCaRt DspNeAc fiifnicg egrepnrionttyipnegs a swsearye. Oreusrp roenssuilbtsl eg rfoour peeadc hSa slemroon-eglrlaou ipso loaft eSsa ilnmtoo n3e clllau.s ters, results also revealed diversity among Salmonella isolates in cluster The out of III (sero-group B). Eighteen than on1e9 Sdarulmg orenseilslata nspcep.. were resistant to oxytetracycline. Five isolates out of 19 showed more Multi-drug resistance was seen only among Salmonella Typhimurium isolates. Enrofloxacin was the most susceptible antibiotic against all isolates in this study. Conclusion: The emergence of multiple antibiotic-resistant strains of Salmonella Typhimurium srehsoiustladn cbee poaft tgerrneas to cf oSnaclmeronn etlol at hiseo lpautebsl iwca. sN foo ucnodr,r ewlhaitciohn i nbdeictwateeesn r eEsRisItCa nfcineg teor panritnimtiincgro abniadl agents was not related to specific genetic background.

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