Leishmania spp. are vector-borne flagellates transferred by sand flies. They cause cutaneous, mucocu- taneous and visceral infections in mammals, especially in humans and dogs. A mature male boxer with ulcerative nodules around his eyes and snout was referred to Small Animal Hospital, Faculty of Veterinary Medicine, Uni- versity of Tehran. Multiple cutaneous lesions were seen in physical examination. Mild leukocytosis, neutrophilia, left shift, lymphopenia, and thrombocytopenia were reported by the laboratory. Diagnosis was confirmed by the obser- vation of amastigotes in blood samples and inside tissue macrophages. The infection was treated using pentavalent antimonial drug for four weeks

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