Title : ( Preperation, characterization and evaluation of physicochemical properties of Phycocyanin-Loaded Solid Lipid Nanoparticles and Nanostructured Lipid Carriers. )
Authors: Fakhri Shahidi , Amin yagoubi , Mohebbat Mohebbi , Mehdi Varidi , Shiva Golmohammadzadeh ,
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Abstract
The aim of this study was to prepare, characterize and evaluate solid lipid nanoparticles (SLN) and nanostructured lipid carriers(NLC) containing phycocyaninfrom Spirulinaplatensis. Thesenanocarrierers were prepared through ultrasound-assisted high-shear homogenization method. The results showed that the type and amount of lipid and surfactant had a significant effect on the particle size distribution, polydispersity index and zeta potential.The results of DSC, FTIR and XRD analyses indicated no phycocyanin peak in the prepared formulations, showingthe effectiveness of SLN and NLC systems in phycocyanin encapsulation. The results ofthe investigations on particles morphology showed that the produced nanoparticles were spherical and uniformed and their sizerangedfrom 50 to 80 nm. The nanoparticleencapsulation efficiency varied from 37 to 69%.
Keywords
, Solid lipid nanoparticles, Nanostructured lipid carriers, Phycocyanin, Spirulinaplatensis.
@inproceedings{paperid:1060973,
author = {Shahidi, Fakhri and Yagoubi, Amin and Mohebbi, Mohebbat and Varidi, Mehdi and Shiva Golmohammadzadeh},
title = {Preperation, characterization and evaluation of physicochemical properties of Phycocyanin-Loaded Solid Lipid Nanoparticles and Nanostructured Lipid Carriers.},
booktitle = {6th international conference on nanotechnology(ICN 2017)},
year = {2017},
location = {دوبی},
keywords = {Solid lipid nanoparticles; Nanostructured lipid carriers; Phycocyanin; Spirulinaplatensis.},
}
%0 Conference Proceedings
%T Preperation, characterization and evaluation of physicochemical properties of Phycocyanin-Loaded Solid Lipid Nanoparticles and Nanostructured Lipid Carriers.
%A Shahidi, Fakhri
%A Yagoubi, Amin
%A Mohebbi, Mohebbat
%A Varidi, Mehdi
%A Shiva Golmohammadzadeh
%J 6th international conference on nanotechnology(ICN 2017)
%D 2017
