Regarding to the high content of polyunsaturated fatty acids in fish tissues, improving the fish antioxidant status seems to be necessary and may be associated with beneficial effects on fish health. The present study aimed to investigate the effects of dietary vitamin C supplementation (20 mg/kg body weight, 4 weeks) on some oxidative status biomarkers in RBC of common carp ( Cyprinus carpio ). The results showed that the activities of antioxidant enzymes including catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD) were not changed significantly following dietary vitamin C supplementation in comparison to the control group. Moreover, dietary vitamin C supplementation for 28 days significantly lowered malondialdehyde (MDA) concentration in erythrocyte haemolysate by approximately 26% compared to that of the control group. In conclusion, dietary vitamin C supplementation appears to be able to protect carp erythrocytes against oxidative stress by decreasing lipid peroxidation.

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