Climate condition is expected to have significant in rodents’ diversity and in the seasonal pattern of diseases that are carried by different rodents. In an effort to aid in the study of the biodiversity of parasites of rodents in different climate zoon we examine climate patterns in the parasite assemblages of different rodents from March 2015 to February 2016. Of 253 captured rodents in three climate zones of Iran, thirteen species of rodents were recognized. Trapped rodents humanely sacrificed and the ga strointestinal and respiratory tracts were removed and examined to identify parasitic helminths. Of 253 rodents examined, 109 (43.08%) were positive for helminth infection including Syphacia obvelata , Aspicularis tetraptera , Trichuris muris , Capillaria sp . , Physaloptera sp , Gongylonema sp., Nippostrongylus brasiliensis , Heligmosomoides polygyrus , Hymenolepis diminuta , Hymenolepis nana , Cysticercus fasciolaris , Mesocestoides sp. larva and Moniliformis moniliformis. Notocotylus neyrai was the only species of trematoda isolated from water vol for the first time in Iran. Some rodents are omnivorous, showing high predisposition to helminths parasites consequently, they harbor some species of parasites which are potentially zoonotic or may serve as vectors of important zoonotic pathogens. T herefore, the potential health hazard of these species needs to be considered to prevent infectivity of humans.

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