Dysona - Life Science, Volume (1), No (2), Year (2020-7) , Pages (91-95)

Title : ( In silico study of dynamic level interaction between CLF36 peptide and coronavirus surface protein in Bovine coronaviruses )

Authors: abdulaziz hamad alahmad , Mojtaba Tahmoorespur , marjan azghandi , zana pirkhezranian ,

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Abstract

Considering the fact that coronavirus is one of the major causes of calf diarrhea syndrome, this study aimedto investigate the interaction between the peptide cLF36 and the coronavirus protein by utilizing computational methods. Coronavirus amino acid sequence was obtained and molecular docking between coronavirus and the engineered camel lactoferrin was performed. The simulation model was conducted using PROMX model. The results showed that the highest bond length was 2.5Å and the lowest 1.7Å which makes the connection between the two proteins strong, robust, and close to reality. According to the obtained results, cLF36 is a promising potential drug in the treatment of calf diarrhea

Keywords

, Keywords:Calf diarrhea, Coronavirus, Camel lactoferrin, Molecular docking simulation
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@article{paperid:1083074,
author = {Hamad Alahmad, Abdulaziz and Tahmoorespur, Mojtaba and Azghandi, Marjan and Pirkhezranian, Zana},
title = {In silico study of dynamic level interaction between CLF36 peptide and coronavirus surface protein in Bovine coronaviruses},
journal = {Dysona - Life Science},
year = {2020},
volume = {1},
number = {2},
month = {July},
issn = {2708-6291},
pages = {91--95},
numpages = {4},
keywords = {Keywords:Calf diarrhea; Coronavirus; Camel lactoferrin; Molecular docking simulation},
}

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%0 Journal Article
%T In silico study of dynamic level interaction between CLF36 peptide and coronavirus surface protein in Bovine coronaviruses
%A Hamad Alahmad, Abdulaziz
%A Tahmoorespur, Mojtaba
%A Azghandi, Marjan
%A Pirkhezranian, Zana
%J Dysona - Life Science
%@ 2708-6291
%D 2020

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